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In small-town Bartow, Florida four bodies are found slaughtered in a factory. It’s the largest mass murder in county history. Each victim is somehow connected to the factory and the family business — and each victim seems to have been executed by a professional assassin. When investigators finally zero in on a prime suspect, they are foiled by his picture-perfect alibi – security footage showing him 500 miles from the scene of the crime. With no hard evidence in sight – and with the bloodthirsty killer still on the loose – investigators turn to video forensic analysis, complex timeline reconstruction, and a most unexpected 3-year-old fingerprint.

On September 29, 1990, the body of twenty-two year old college student, Linda Yalem, is discovered off a bike path in a suburb of Buffalo, New York. Yalem has been raped and strangled with a garrote. DNA evidence recovered from her body allows police to link the crime to six other recent rapes in the Buffalo area. But other than DNA evidence police have little to go on; the murderer remains at large. Over the next sixteen years, attacks slow but do not stop. There is another rape and two more murders. Then advances in DNA technology and clues culled from unsolved rape cases lead police to the unlikely killer and rapist. He’s Buffalo suburbanite, Altemio Sanchez. Sanchez is a pillar of the community: married, with two children, and active in church and Little League.

On the outskirts of Hamilton, Ontario, a jogger makes a gruesome discovery – the partially mummified remains of a human body. Using state of the art forensics, police are able to identify the body as that of a suburban wife and mother of two. She has been brutally bludgeoned to death, but no missing person’s report has ever been filed. As police investigate, they discover evidence of domestic strife, including a love triangle and charges of assault. Determined to find the killer, police dig further into the victim’s life, doggedly tracking down a former lover to New York City, where they uncover another crime. But it is a forensic entomologist and her knowledge of the minute lives of insects that leads investigators back to Ontario and the arrest of the woman’s husband for murder.

A series of over sixty spectacular fires rips through California’s San Joaquin valley, killing four people and devastating the landscape. An extensive investigation by the ATF, police and forensic scientists reveals a common pattern among all the blazes, and to their horror, authorities soon realize that a serial arsonist is on the loose. As they painstakingly study the evidence from each crime scene, a single fingerprint leads them to one suspect. He is John Leonard Orr, a respected arson investigator for the Glendale Fire Department in Southern California and one of the worst serial arsonists of the 20th century.

Glamorous Las Vegas, Nevada is famous for wealth, lady luck and second chances. But when homicide detectives discover the charred remains of a prominent business man, Sin City reveals a darker side. With a long list of suspects and millions of dollars on the line, investigators are suddenly thrust into a dangerous world of high stakes deception fueled by passion, greed and revenge. A murder mystery where nothing is as it seems and anyone is capable of anything, only forensic science can expose the truth and catch the killer.

A series of bombings and bank robberies have left the usually serene city of Spokane, Washington reeling. Claiming responsibility for the reign of terror, is a deadly, almost invisible sect called the Phineas Priests who seem to strike at will. The phantom cell, driven by a perverted code of hate is considered be the most radical and dangerous in the entire white supremacist movement. Although the gunmen are masked and leave few clues, an FBI forensic photo analysis team, working with high quality bank surveillance footage, slowly starts to get a clearer picture of the assailants. The question is, can they find them before they strike again?

April, 1992. An elderly couple is found dead in the trunk of their car at their home in upscale Toronto. The investigation eventually leads authorities to the couple’s vacation home one hour north of the city. Police soon learn of the “House Hermit”- a mysterious intruder breaking into area cottages and camping in them. He becomes the prime suspect in the murders, but though police finally identify him they cannot find him anywhere. That’s because he’s moved 3,000 miles away to Vancouver, where he abducts and assaults three women before finally being caught red handed,tstrangling one of his victims.

For 23 days in October, 2002 a sniper terrorizes the Washington DC area, shooting thirteen people and killing ten. The victims are ordinary people doing routine activities. Nothing links them; they are chosen at random. Police mount one of the largest investigations in American history to catch a ruthless and elusive killer. In the end, their most productive clue comes from the sniper himself, who calls a police tip line and brags about a previous shooting in Alabama. Authorities are able to recover a single fingerprint from that crime, which eventually leads them to not one, but two killers, including a seventeen year old boy.

A retired fireman on a morning bike ride notices a burning bundle in a farmer’s field…and recognizes the smell of burning human flesh. Investigators at the scene find an unrecognizable body, a distinctive lighter, 2 pairs of latex gloves and the box they came in, paper towels and torn scraps of an office memo. State of the art forensics, dogged police work, and some extraordinary turns of events lead police to the murder scene – the medical room of a ball bearings factory, and the arrest of a former Armenian mafia thug turned English family man for the brutal murder of his cruel ex-boss.

The 1996 Summer Olympics in Atlanta, Georgia are rocked by a massive pipe bomb explosion. A woman is killed and hundreds injured. Subsequent bombs at an abortion clinic and a gay bar show a similar M.O., and increasing refinement. Police have no clue who is behind the bombings until they receive a letter signed by ‘The Army of God’, an anti-abortion, anti-gay, white supremacist group. When another abortion clinic is bombed in Birmingham, Alabama, a witness sees a suspicious man leaving the scene and gets his license number. Police are soon on the trail of Christian extremist Eric Rudolph, but it will take a five year manhunt through the rugged terrain of the Natahala National Forest before they can catch America’s Most Wanted criminal.